当前位置:首页 > 研发平台 > 重点实验室  > 团队成员 

团队成员

庄秋宇

更新时间:


庄秋宇:

理学博士,福建医科大学孟超肝胆医院助理研究员,福州大学硕士生导师。主持国家自然科学基金、福建省自然科学基金、福建省卫健委中青年骨干人才培养项目等多个国家/省部级项目入选福建省高层次人才(B类)。

 

研究方向

肿瘤相关细胞信号转导通路、肿瘤免疫治疗

 

主持承担的科研项目:

  1. RNA2位氧甲基修饰在肝癌免疫逃逸中的作用及机制研究,福建省卫健委中青年骨干人才培养项目,2021/01-2023/12,主持。

  2. 基于HSV-1溶瘤病毒的免疫联合疗法用于肝癌治疗的研究,福建省科技创新联合资金引领项目,2021/08-2024/08,主持。

  3. 2’-O-甲基转移酶FTSJ3通过调控I型干扰素促进肝癌免疫逃逸的机制研究,国家自然科学基金(青年)项目,2022/01-2024/12,主持。

  4. 表达SIRPα-SLAMF7嵌合受体的巨噬细胞的抗肿瘤作用研究,福州市科技计划项目科技创新创业人才培育计划项目,2022/06-2024/06,主持。

 

已发表论文:

  1. Da Zhang, Chenwei Jiang, Xiaoyuan Zheng, Zhiwen Lin, Qiuyu Zhuang, Huanzhang Xie, Yuzhi Liang et al. "Normalization of Tumor Vessels by Lenvatinib‐Based Metallo‐Nanodrugs Alleviates Hypoxia and Enhances Calreticulin‐Mediated Immune Responses in Orthotopic HCC and Organoids." Small (2023): 2207786.

  2. Yunhao Wang, Qingfu Zhao, Binyu Zhao, Youshi Zheng, Qiuyu Zhuang, Naishun Liao, Peiyuan Wang et al. "Remodeling Tumor‐Associated Neutrophils to Enhance Dendritic Cell‐Based HCC Neoantigen Nano‐Vaccine Efficiency." Advanced science 9, no. 11 (2022): 2105631.

  3. Cuilin Zhang#, Qiuyu Zhuang#, Jingfeng Liu, and Xiaolong Liu. "Synthetic biology in chimeric antigen receptor T (CAR T) cell engineering." ACS Synthetic Biology 11, no. 1 (2022): 1-15.(#共同第一作者)

  4. Daowei Yang, Yaoji Liang, Shubo Zhao, Yan Ding, Qiuyu Zhuang, Qilin Shi, Tingting Ai, Su-Qin Wu, and Jiahuai Han. "ZBP1 mediates interferon-induced necroptosis." Cellular & molecular immunology 17, no. 4 (2020): 356-368.

  5. Antonio Totaro#, Qiuyu Zhuang#, Tito Panciera, Giusy Battilana, Luca Azzolin, Giulia Brumana, Alessandro Gandin, Giovanna Brusatin, Michelangelo Cordenonsi, and Stefano Piccolo. "Cell phenotypic plasticity requires autophagic flux driven by YAP/TAZ mechanotransduction." Proceedings of the National Academy of Sciences 116, no. 36 (2019): 17848-17857.(#共同第一作者)

  6. Hanjie Li#, Qiuyu Zhuang#, Yuze Wang#, Tianying Zhang, Jinghua Zhao, Yali Zhang, Junfang Zhang et al. "HBV life cycle is restricted in mouse hepatocytes expressing human NTCP." Cellular & molecular immunology 11, no. 2 (2014): 175-183.(#共同第一作者)